Myeloid phagocytes have evolved to rapidly recognize invading pathogens and clear them through opsonophagocytic killing.The adenylate cyclase toxin (CyaA) of Bordetella pertussis and the edema toxin (ET) of Bacillus anthracis are both calmodulin-activated toxins with adenylyl cyclase activity that invade host cells and massively increase the cellul

Abstract Background Glioma is the most commonly diagnosed malignant and aggressive brain cancer in adults.Traditional researches mainly explored the expression profile of glioma at cell-population level, but ignored the heterogeneity and interactions of among glioma cells.Methods Here, we firstly analyzed the single-cell RNA-seq (scRNA-seq) data of

dresses BackgroundAtrial fibrillation (AF) is a major risk factor for ischemic stroke unless treated with an anticoagulant.Detecting AF can be difficult because AF is often paroxysmal and asymptomatic.The aims of this study were to develop a screening model to detect AF in a primary healthcare setting and to initiate oral anticoagulant therapy in h

Hajj, a unique yearly mass gathering pilgrimage of more than 2 million Muslims from around the world, presents enormous challenges to the Saudian Arabia government.The potential for Supplements deadly epidemic outbreaks of bacterial and viral diseases leading to upper respiratory infection and meningitis and human stampedes call for prompt attentio